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Mapping Data
Experiment
  • Experiment
    TEXT-Physical Mapping
  • Chromosome
    18
  • Reference
    J:2592 Eccles MR, Genes encoding the platelet-derived growth factor (PDGF) receptor and colony-stimulating factor 1 (CSF-1) receptor are physically associated in mice as in humans. Gene. 1991 Dec 15;108(2):285-8
  • ID
    MGI:40087
Genes
GeneAlleleAssay TypeDescription
Pdgfrb Southern analysis 3'Pdgfrb cDNA and 3'Pdgfrb cDNA
Csf1r Southern analysis 5'Csfmr cDNA
Notes
  • Reference
    Revised gene symol: Pdgfrb (formerly Pdgfr).
  • Experiment
    Physical mapping data suggested that the Pdgfrb gene maps 5' to the Csmfr gene. Sequential Southern analysis of ClaI digested BALB/c DNA detected bands of 90 and 425kb with a 5'Pdgfrb cDNA probe and a 425kb band using a 3'Pgfrb cDNA probe or a 5'Csfmr cDNA probe. Using SmaI digested BALB/c DNA, a 70kb fragment was detected with both the 3'Pdgfrb cDNA probe and the 5'Csfmr cDNA probe. These data indicate a maximum separation of 70kb between these loci. However, because the 3'Pdgfrb probe contains nearly half of the Pdgfrb cDNA rather than just the end, it is likely that these loci are much closer and may be separated by a distance similar to that in humans (less than 500bp).

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory