Mapping Data

Experiment

• Experiment
  TEXT-QTL-Candidate Genes
• Chromosome
  17
• Reference
  J:97908 Baxter AG, et al., Genetic control of susceptibility to autoimmune gastritis. Int Rev Immunol. 2005 Jan-Apr;24(1-2):55-62
• ID
  MGI:3655736

Genes

Gene	Assay Type
Gasa4	reported elsewhere

Notes

• Experiment
  Previous study with thymectomized (BALB/cCrSlc x C57BL/6)F2 animals mapped susceptibility to autoimmune gastritis to mouse Chromosome 4 (Gasa1, Gasa2), Chromosome 6 (Gasa3), and Chromosome 17 (Gasa4). Three of these loci map near other autoimmune QTLs.
  
  On mouse Chromosome 4, Gasa1 at 72.5 cM maps near diabetes QTL Idd11 at 64.6 cM. Gasa2 at 77.5 cM maps near diabetes QTL Idd9. Gasa2 was found to interact epistatically with an oophoritis susceptibility QTL on mouse Chromosome 1 named Aod3 (63 cM), and also with Gasa4 on chromosome 17 near the H2 locus. Tnfrsf18 is a potential candidate genes mapping near Gasa2.
  
  Gasa4 maps near an H2-linked locus on mouse Chromosome 17 associated with diabetes susceptibility in NOD x C3H animals.