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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    1
  • Reference
    J:78754 Beamer WG, et al., Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice. J Bone Miner Res. 2001 Jul;16(7):1195-206
  • ID
    MGI:2389144
Genes
GeneAlleleAssay TypeDescription
Bmd5 visible phenotype
D1Mit14
Notes
  • Experiment
    Linkage analysis was performed on 986 (C57BL/6J x C3H/HeJ)F2 female animals using 107 microsatellite markers to identify QTLs associated with bone mineral density (BMD). Parental strain C3H/HeJ exhibits higher bone mineral density values compared to C57BL/6J. Bmd5 mapped to 81.6 cM on mouse Chromosome 1 with a peak LOD=24.44 at D1Mit14 in linkage to femoral and vertebral BMD. The QTL range of Bmd5 spans 52 cM - 106.3 cM. C3H/HeJ-derived alleles confer an additively-inherited increase in femoral and vertebral BMD at Bmd5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory