Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
• ID
  MGI:2386714

Genes

Gene	Assay Type
Tshp1	visible phenotype
Tshp2	visible phenotype
D1Mit11	PCR amplified length variant
D1Mit14	PCR amplified length variant

Notes

• Experiment
  76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. QTLs affecting tooth shape, Tshp1 and Tshp2, mapped to mouse Chromosome 1. The Tshp1 interval spans 58.7 cM - 81.6 cM and the Tshp2 interval is centered around 81.6 cM on chromosome 1. Both tooth size QTLs exceed the P<0.001 significance threshold of LOD=4.185.