Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  3
• Reference
  J:40854 Belknap JK, et al., Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice. Behav Genet. 1997 Jan;27(1):55-66
• ID
  MGI:1932409

Genes

Gene	Assay Type
D3Mit17	PCR amplified length variant
Letohc1	visible phenotype
Adh1	reported elsewhere

Notes

• Experiment
  Ethanol consumption in mice was analyzed in selectively breed mice derived from an F2 population of intercrossed (C57BL/6J x DBA/2J)F1 mice. Whereas C57BL/6J are high consumers of alcohol and DBA/2J are low consumers. The concentration of ethanol used was 10%. With low preference mice and high preference mice mated for a maximum of 4 generations. In generation 4 of the Low selected line a significant QTL was observed and associated with D3Mit17. Authors suggest Adh1 may be a candidate gene.