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Inbred Strains of Mice: MYD


Inbr (Le) MYD is N7F12, MYD-+/+ is F71. Agouti: +. Origin Mutation to myd (myodystrophy) occurred in 1963 in ls (lethal spotting) stock from R.Phillips in 1961. Crossed to C57BL/6J-AwJ, then b x s. Os from ROP crossed to +/+ and to myd/+ (N7). Maintained as Os,+/+,myd balanced stock. A +/+ substrain was derived at F35. myd homozygotes have a progressive and diffuse myopathy of all skeletal muscles and die between 5 wks. and 5 months. Maint. by J as frozen embryos..

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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