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Inbred Strains of Mice: LPT


Inbr (Le) 89. Colour: agouti. Origin: Mutation to loop-tail (Lp) arose in strain A in 1949. From W.Hollander to Snell 1950. Crossed 7 times to C57BL/6J, once to C3H/He, then b x s. To Lane 1969. Loop-tail is a semi-dominant mutation with Lp/+ mice having crooked or looped tails and some head wobbling. Homozygotes die at birth. Maint. by Le.

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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