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Inbred Strains of Mice: LLC


Inbr (Ckc) 46. Colour ?. Origin: Chai 1976. Selected for low leukocyte count from a cross involving C57BL/6J, C57BR/cdJ, A/J, BALB/cJ, LG/J, and SM/Ckc (see also HLC).


Mean leukocyte count now 4000-5000/cu mm. Mice over 10-18 months have amyloid deposits in the spleen and kidney and most show reticular cell hypoplasia. Rare spontaneous myoepitheliomas arising from myoepithelial cells of various exocrine glands have been observed in LLC.A/Ckc (Sundberg et al 1991). Maint. by Ckc.

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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