About   Help   FAQ
Phenotype Images associated with this Gene
Symbol
Name
ID 		Lama1
laminin, alpha 1
MGI:99892


8 phenotype image(s) for Lama1 alleles
Showing image(s) 1 to 8
Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

Caption: Lama1nmf223/Lama1nmf223 mutants exhibit vitreal and retinal abnormalities (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice have a similar but more severe retinal phenotype than Lama1nmf223/Lama1nmf223 mice (details)
Represented Alleles:
Edil3Tg(Sox2-cre)1Amc, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Lama1tm1Olf, laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Peripheral retinal degeneration is observed in Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice as early as 4 weeks of age (details)
Represented Alleles:
Edil3Tg(Sox2-cre)1Amc, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Lama1tm1Olf, laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Lama1nmf223/Lama1tm1.1Olf mice experience vitreal fibroplasia and vessel tortuosity (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Lama1tm1.1Olf, laminin, alpha 1; targeted mutation 1.1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Primary inner limiting membrane abnormalities are evident in Lama1nmf223/Lama1nmf223 mice (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Peripheral inner nuclear layer cell loss is associated with reduced electroretinogram responses in Lama1nmf223/Lama1nmf223 mice (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: Altered development of astrocytes and blood vessels in Lama1nmf223/Lama1nmf223 retinas (details)
Represented Alleles:
Lama1nmf223, laminin, alpha 1; neuroscience mutagenesis facility, 223
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Caption: The inner limiting membrane does not form in Lama1tm1Olf/Lama1tm1Olf Edil3Tg(Sox2-cre)1Amc/0 mice (details)
Represented Alleles:
Edil3Tg(Sox2-cre)1Amc, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Lama1tm1Olf, laminin, alpha 1; targeted mutation 1, Olivier Lefebvre
Copyright: This image is from Edwards MM, J Biol Chem 2010 Mar 5;285(10):7697-711 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160722
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory