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Phenotype Images associated with this Gene
Symbol
Name
ID 		b2b1468Clo
Mutant line 1468, Cecilia Lo
MGI:5696348


16 phenotype image(s) for b2b1468Clo alleles
Showing image(s) 1 to 10 		Show   figures per page Next Last
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Click on allele symbol for full phenotype details.

Caption: Mutant 1468-003-4 (E15.5) displays right aortic arch, hypoplastic transverse arch, and malpositioning of the great arteries which is diagnosed as double outlet right ventricle (DORV) by ECM histopathology. (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D ECM image stack of 1468-003-4 (E15.5) in coronal plane reveals double outlet right ventricle (DORV) {S,D,D}, right aortic arch (RAA), hypoplastic transverse aortic arch, spongy right ventricle, and dilated atria.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D micro-CT image stack in the coronal plane of 1468-003-4 (E15.5) reveals DORV, subaoctic VSD, right aortic arch
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Kidneys of mutant 1468-003-4 are hydronephrotic and hydroureter. Some glomerular cysts are present (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1468-003-1 (E 15.5) is runted with small eyes (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant 1468-003-1 (E15.5) presents with a small right ventricle confirmed by ECM histopathology. (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D EFIC image stack in the coronal plane of 1468-003-1 (E15.5) reveals hypoplastic right ventricle with normal pulmonary artery size.
Click thumbnail to play movie. (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Kidneys of mutant 1468-003-1 shows glomerular and tubular cysts as well as hydronephrosis and hydroureter (details)
Represented Alleles:
b2b1468Clo, Mutant line 1468, Cecilia Lo; Bench to Bassinet Program (B2B/CVDC), mutation 1468 Cecilia Lo
Cntrlb2b1468.1Clo, centriolin; Bench to Bassinet Program (B2B/CVDC), mutation 1468, subline 1 Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory