Phenotype Images associated with this Other Genome Feature

About Help FAQ

Phenotype Images associated with this Other Genome Feature

Symbol
Name
ID

Igs1
intergenic site 1
MGI:5319510

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Retinal vascular defects in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 mice (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Inhibition of vascular growth and production of excess tip cells in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinas (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: In developing Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinas, large regions of the endothelial cell network are not perfused (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Altered vascular development in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinas (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Interstitial tip cells in adult Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Pdgfra-cre)1Clc/0 retinas (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Pdgfra-cre)1Clc, transgene insertion 1, Constance L Cepko Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Spatially localized Edn2 expression results in local inhibition of retinal vascular development in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Pax6-cre,GFP)2Pgr/0 mice (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Pax6-cre,GFP)2Pgr, transgene insertion 2, Peter Gruss Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Inhibition of vascular development and midgestational lethality in Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Edil3^{Tg(Sox2-cre)1Amc}/0 embryos (details) Represented Alleles: Edil3^{Tg(Sox2-cre)1Amc}, EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Increased filopodia density in the interior of the Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(Six3-cre)69Frty/0 retinal vascular plexus at P7 (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(Six3-cre)69Frty, transgene insertion 69, Yasuhide Furuta Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Absence of vascular defects in the skin of adult Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Tg(KRT5-cre)5132Jlj/0 mice (details) Represented Alleles: Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Tg(KRT5-cre)5132Jlj, transgene insertion 5132, Jose Luis Jorcano Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133
	Caption: Absence of vascular defects in the brains of embryonic day 18 Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}/Igs1⁺ Foxg1^tm1(cre)Skm/Foxg1⁺ (details) Represented Alleles: Foxg1^tm1(cre)Skm, forkhead box G1; targeted mutation 1, Susan K McConnell Igs1^{tm11(CAG-Bgeo,-Edn2)Nat}, intergenic site 1; targeted mutation 11, Jeremy Nathans Copyright: This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23