About   Help   FAQ
Phenotype Images associated with this Gene
Symbol
Name
ID 		Spg11
SPG11, spatacsin vesicle trafficking associated
MGI:2444989


7 phenotype image(s) for Spg11 alleles
Showing image(s) 1 to 7
Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

Caption: Spastic and ataxic gait in Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu mice (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Caption: Severe neuron loss in the motor cortex and the cerebellum of Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu mice (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Caption: Accumulation of autofluoerscent material and activation of astrocytes in different regions of the central nervous system of Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu mice (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Caption: Purkinje cells in Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu mice accumulate abnormal autolysosomes (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Caption: Regeneration of lysosomes in Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu MEFs is decreased (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Caption: Reduced lysosome numbers in Purkinje cells of Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu mice are consistent with impaired autophagic lysosome reformation (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Caption: Autolysosomes and lipofuscin-like material in different brain regions of Spg11Gt(EUCE0085f05)Hmgu/Spg11Gt(EUCE0085f05)Hmgu mice (details)
Represented Alleles:
Spg11Gt(EUCE0085f05)Hmgu, SPG11, spatacsin vesicle trafficking associated; gene trap EUCE0085f05, Helmholtz Zentrum Muenchen GmbH
Copyright: This image is from Varga RE, PLoS Genet 2015 Aug;11(8):e1005454, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:228803
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory