Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Npc1
NPC intracellular cholesterol transporter 1
MGI:1097712

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	Caption: Loss of Purkinje cells in the cerebellum and presence of foam cells in the liver and spleen of Npc1^tm1Mbjg/Npc1^tm1Mbjg mice (details) Represented Alleles: Npc1^tm1Mbjg, NPC intracellular cholesterol transporter 1; targeted mutation 1, Joseph L Goldstein Copyright: This image is from Xie X, Proc Natl Acad Sci U S A 2011 Sep 13;108(37):15330-5. Copyright 2011 National Academy of Sciences, U.S.A. J:176587
	Caption: Abnormal morphology of Npc1^m1N/Npc1^m1N sperm (details) Represented Alleles: Npc1^m1N, NPC intracellular cholesterol transporter 1; Niemann Pick type C1 NIH Copyright: This image is from Fan J, Mol Reprod Dev 2006 Oct;73(10):1284-91, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:119302
	Caption: Analysis of Npc1^m1N/Npc1^m1N testes indicates partially blocked spermatogenesis (details) Represented Alleles: Npc1^m1N, NPC intracellular cholesterol transporter 1; Niemann Pick type C1 NIH Copyright: This image is from Fan J, Mol Reprod Dev 2006 Oct;73(10):1284-91, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:119302
	Caption: Neurodegenerative changes affecting cerebullar Purkinje cells of Npc1^m1N/Npc1^m1N, Npc2^tm1Plob/Npc2^tm1Plob, and double homozygous mice for Npc1^m1N and Npc2^tm1Plob (details) Represented Alleles: Npc1^m1N, NPC intracellular cholesterol transporter 1; Niemann Pick type C1 NIH Npc2^tm1Plob, NPC intracellular cholesterol transporter 2; targeted mutation 1, Peter Lobel and David Sleat Copyright: This image is from Sleat DE, Proc Natl Acad Sci U S A 2004 Apr 20;101(16):5886-91. Copyright 2004 National Academy of Sciences, U.S.A. J:89617

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