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Phenotype Images associated with this Gene
Symbol
Name
ID
Yap1
yes-associated protein 1
MGI:103262


12 phenotype image(s) for Yap1 alleles
Showing image(s) 1 to 10
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Caption: Lethal cardiomyopathy in Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice (details)
Represented Alleles:
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Yap1tm1.1Eno, yes-associated protein 1; targeted mutation 1.1, Eric N Olson
Copyright: This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670
Caption: Cardiomyopathy in Wwtr1tm1.2Eno/Wwtr1tm1.2Eno Yap1tm1.1Eno/Yap1+ Tg(Myh6-cre)2182Mds/0 mice (details)
Represented Alleles:
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Wwtr1tm1.1Eno, WW domain containing transcription regulator 1; targeted mutation 1.1, Eric N Olson
Yap1tm1.1Eno, yes-associated protein 1; targeted mutation 1.1, Eric N Olson
Copyright: This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670
Caption: Cardiomyopathy in Wwtr1tm1.2Eno/Wwtr1+ Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice (details)
Represented Alleles:
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Wwtr1tm1.1Eno, WW domain containing transcription regulator 1; targeted mutation 1.1, Eric N Olson
Yap1tm1.1Eno, yes-associated protein 1; targeted mutation 1.1, Eric N Olson
Copyright: This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670
Caption: Impaired neonatal heart regeneration in Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice (details)
Represented Alleles:
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Yap1tm1.1Eno, yes-associated protein 1; targeted mutation 1.1, Eric N Olson
Copyright: This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670
Caption: Wwtr1tm1.1Eno/Wwtr1tm1.1Eno Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice exhibit cardiac abnormalities and Wwtr1tm1.1Eno/Wwtr1+ Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 hearts show defects in proliferation and survival (details)
Represented Alleles:
Tg(Myh6-cre)2182Mds, transgene insertion 2182, Michael D Schneider
Wwtr1tm1.1Eno, WW domain containing transcription regulator 1; targeted mutation 1.1, Eric N Olson
Yap1tm1.1Eno, yes-associated protein 1; targeted mutation 1.1, Eric N Olson
Copyright: This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670
Caption: Abnormal kidney development in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ (details)
Represented Alleles:
Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon
Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill
Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
Caption: Abnormal nephron formation in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details)
Represented Alleles:
Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon
Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill
Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
Caption: Impaired nephron induction in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ mice (details)
Represented Alleles:
Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon
Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill
Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
Caption: S-shaped body is reduced in size in Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ nephrons (details)
Represented Alleles:
Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon
Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill
Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266
Caption: Nephrogenesis abnormalities in Wwtr1tm1Hmc/Wwtr1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+, Yap1tm1Hmc/Yap1tm1Hmc Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+ and double mutant mice (details)
Represented Alleles:
Six2tm1(tTA,tetO-EGFP/cre)Amc, sine oculis-related homeobox 2; targeted mutation 1, Andrew P McMahon
Wwtr1tm1Hmc, WW domain containing transcription regulator 1; targeted mutation 1, Helen McNeill
Yap1tm1Hmc, yes-associated protein 1; targeted mutation 1, Helen McNeill
Copyright: This image is from Reginensi A, PLoS Genet 2013 Mar;9(3):e1003380, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195266

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory