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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnah5b2b2451Clo
Name: dynein, axonemal, heavy chain 5; Bench to Bassinet Program (B2B/CVDC), mutation 2451 Cecilia Lo
MGI ID: MGI:5645238
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2451-002-LA exhibits heterotaxy with levocardia, levogastria, but right sided pancreas and malrotated gut.Dnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo
Mutant 2451-002-LA exhibits heterotaxy levogastria, but right sided pancreas and spleen.Dnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo
Mutant 2451-002-LA shows kidney positioning consistent with situs solitus.Dnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo
Serial 2D ECM image stack in the coronal plane of 2451-002-LA reveals dual inferior vena cava (IVC).
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Dnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo
EFIC SummaryDnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo
Mutant 2451-002-LA exhibits tracheal airway epithelia with slow dyskinetic and immotile cilia.
Click thumbnail to play movie.
Dnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo
Mutant 2451-002-LA exhibits tracheal airway epithelia with slow dyskinetic and immotile cilia.
Click thumbnail to play movie.
Dnah5b2b2451Clo/Dnah5b2b2451CloC57BL/6J-Dnah5b2b2451Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory