Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Qsox1^b2b2673Clo
Name:	quiescin Q6 sulfhydryl oxidase 1; Bench to Bassinet Program (B2B/CVDC) mutation 2673, Cecilia Lo
MGI ID:	MGI:5615575

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Mutant (E16.5) exhibits persistent truncus arteriosis (PTA) which was confirmed by ECM histopathology.	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Mutant (E16.5) shows hypoplastic thymus and malrotated heart.	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	EFIC Summary	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Serial 2D ECM stack of mutant in the coronal plane reveals persistent truncus arteriosis (PTA), atrioventricular septal defect (AVSD), tracheoesophageal fistula, aberrant subclavian artery forming incomplete vascular ring, left atrial isomerism, and biventricular hypertrophy. Click thumbnail to play movie.	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Mutant (E16.5) presents with micropthalmia, short snout, microganthia, and preaxial digit duplication.	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Mutant (E16.5) exhibits a hypoplastic thymus	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Mutant (E16.5) presents with a hypoplastic spleen	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	EFIC Summary	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Serial 2D ECM stack of mutant (ED16.5) in the coronal plane reveals atrioventricular septam defect (AVSD) with dual inferior vena cava (IVC). Click thumbnail to play movie.	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo
	Mutant (E16.5) presents with hydrops, petechiae, bilateral anopthalmia, agnathia, and short snout	Qsox1^b2b2673Clo/Qsox1^b2b2673Clo	C57BL/6J-Qsox1^b2b2673Clo

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