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Phenotype Images associated with this Allele
Nomenclature
Symbol: Trappc10b2b2416Clo
Name: trafficking protein particle complex 10; Bench to Bassinet Program (B2B/CVDC) mutation 2416, Cecilia Lo
MGI ID: MGI:5560902
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2416-004-NB shows a hypoplastic thymus and thickened ventricular walls which is diagnosed as biventricular hypertrophy by EFIC imagingTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
EFIC SummaryTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Serial EFIC image stack of 2416-004-NB in the coronal plane reveals AVSD and biventricular hypertrophy
Click thumbnail to play movie.
Trappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Mutant 2416-004-NB presents with anencephaly, anopthalmia, no nostrils, agnathia, no earsTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Mutant 2416-003-NA shows outflow tract malalignment with hypoplastic ascending aorta and possible hypoplastic aorta and pulmonary artery and thin RV myocardiumTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
EFIC SummaryTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Serial EFIC image stack of 2416-003-NA in the coronal plane reveals perimembranous VSD, aberrant right subclavian artery forming incomplete vascular ring
Click thumbnail to play movie.
Trappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
2D Serial microMRI image of 2416-003-NA in the coronal plane reveals craniofacial hypoplasia, bilateral anophthalmia, and holoprosencephaly
Click thumbnail to play movie.
Trappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Mutant 2416-003-NA shows holoprosencephaly, no mouth opening, anophthalmia, agnathia, and low-set earsTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Mutant 2416-003-NA presents with a hypoplastic thymusTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Mutant 2416-002-NA presents with thickened ventricles which is diagnosed as biventricular hypertrophy by EFIC imagingTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
EFIC SummaryTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Serial 2D EFIC image stack in the coronal plane of 2321-002-NA (E16.5) shows perimembranous VSD and thickened ventricular wall
Click thumbnail to play movie.
Trappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Serial 2D micro-MRI image stack of 2416-002-NA in the coronal plane reveals perimembranous VSD, craniofacial hypoplasia, bilateral anophthalmia, and holoprosencephaly
Click thumbnail to play movie.
Trappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo
Mutant 2416-002-NA exhibits craniofacial hypoplasia comprising anophthalmia, low-set ears, with proboscisTrappc10b2b2416Clo/Trappc10b2b2416CloTrappc10b2b2416Clo

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory