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Phenotype Images associated with this Allele
Nomenclature
Symbol: Drc1b2b2237Clo
Name: dynein regulatory complex subunit 1; Bench to Bassinet Program (B2B/CVDC), mutation 2237 Cecilia Lo
MGI ID: MGI:5552738
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 2237-004-NA shows situs inversus totalis with dextrocardia, inverted outflow, inverted lung and liver lobation, dextrogastria as well as biventricular hypertrophy that was confirmed by EFIC imagingDrc1b2b2237Clo/Drc1b2b2237CloC57BL/6J-Drc1b2b2237Clo
EFIC SummaryDrc1b2b2237Clo/Drc1b2b2237CloC57BL/6J-Drc1b2b2237Clo
Serial 2D EFIC image stack in the coronal plane of 2237-004-NA shows mirror image dextrocardia {I,L,I} and biventricular hypertrophy
Click thumbnail to play movie.		Drc1b2b2237Clo/Drc1b2b2237CloC57BL/6J-Drc1b2b2237Clo
Serial 2D micro-MRI image stack of 2237-004-NA in the coronal plane reveals situs inversus totalis
Click thumbnail to play movie.		Drc1b2b2237Clo/Drc1b2b2237CloC57BL/6J-Drc1b2b2237Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory