 | Mutant 1941-003-2 (E15.5) shows persistent truncus arteriosus (PTA) and high aortic arch | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-2 (E15.5) shows cleft palate | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | EFIC Summary | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Serial 2D EFIC image stack of 1941-003-2 (E15.5) in the coronal plane reveals PTA (Van Praagh type A-2), atrioventricular septal defect (AVSD), and biventricular hypertrophy
Click thumbnail to play movie. | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-NA exhibits a single outflow tract, which was shown to be persistent truncus arteriosus (PTA) by EFIC histopathology analysis | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-NA has no thymus | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-NA shows ambiguous lung lobation with 4 lobes on the right and none on the left | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-NA exhibits a hypoplastic spleen | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Serial micro-MRI image stack of 1941-003-NA in the coronal plane reveals PTA (van Praagh type A-4)
Click thumbnail to play movie. | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | MAPCA: major aortopulmonary collateral artery | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Serial 2D EFIC image stack in the coronal plane of 1941-003-NA shows PTA (Type A-2), atrioventricular septal defect (AVSD) and biventricular hypertrophy
Click thumbnail to play movie. | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-1 (E15.5) shows transposition of the great arteries (TGA), small right ventricle (RV) and left ventricular (LV) hypertrophy | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-003-1 (E15.5) has a cleft palate | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | EFIC Summary | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Serial 2D EFIC image stack in the coronal plane of mutant 1941-003-1 (E15.5) reveals D-transposition of the great arteries (D-TGA), small right ventricle (RV), and left ventricular (LV) hypertrophy
Click thumbnail to play movie. | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-002-1 (E14.5) exhibits a right aortic arch, persistent truncus arteriosus (PTA) and hypoplastic right ventricle (RV) | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | EFIC Summary | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Serial 2D EFIC image stack of 1941-002-1 (E14.5) in the coronal plane reveals quadricusp conotruncal valve, ventricular septal defect (VSD), pulmonary atresia, major aortopulmonary collateral arteries (MAPCA) from root of left carotid artery branch, right aortic arch, aberrant left subclavian artery forming incomplete vascular ring, tracheal-esophageal fistula, hypoplastic lung
Click thumbnail to play movie. | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-004-NA is athymic, and has transposition of the great artieries with high right aortic arch | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-004-NA exhibits hypoplastic spleen | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Mutant 1941-004-NA exhibits duplex kidney and hydronephrosis | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | EFIC Summary | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
 | Serial 2D EFIC image stack of 1941-004-NA in the coronal plane reveals persistent truncus arteriosus (PTA, Type A2), atrioventricular septal defect (AVSD), right sided and high aortic arch (RAA)
Click thumbnail to play movie. | b2b1941Clo/b2b1941Clo | C57BL/6J-b2b1941Clo |
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