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Phenotype Images associated with this Allele
Nomenclature
Symbol: Daw1b2b1584Clo
Name: dynein assembly factor with WDR repeat domains 1; Bench to Bassinet Program (B2B/CVDC), mutation 1584 Cecilia Lo
MGI ID: MGI:5431501
Synonyms: Nebulous
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1584-004-LC displays heterotaxy indicated by dextrocardia, right aortic arch, dual IVC and levogastriaDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
EFIC SummaryDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Serial 2D EFIC image stack in the coronal plane of 1584-004-LC reveals heterotaxy, dextrocardia, perimembranous VSD, {A,L,I}, bilateral IVC connected to right and left side atrium, abnormal lung lobation pattern
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Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Mutant 1584-004-LA with dextrocardia, right aortic arch, dual IVC and midline liverDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Mutant 1584-004-LA displays heterotaxy indicated by dextrocardia, abnormal lung lobation and dextrogastriaDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
1584-004-LA mutant with slow dyskinetic airway cilia motility
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Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Mutant 1584-002-3 (E16.5) displays situs inversus totalDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
EFIC SummaryDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Serial 2D EFIC image stack in the coronal plane of 1584-002-3 (E16.5) reveals mirror image dextrocardia {ILI}
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Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Serial 2D EFIC image stack in the coronal plane of mutant fetus 1584-002-1 (E16.5) reveals DORV {SDD}
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Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Ultrasound color flow imaging in the frontal view of fetus 1584-002-1 (E16.5) shows the aorta and pulmonary artery are side by side emerging from the RV, indicating DORV
Click thumbnail to play movie.
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
A still frame of ultrasound color flow imaging in the frontal view of fetus 1584-002-1 (E16.5) shows the aorta and pulmonary artery are side by side emerging from RV, indicating DORVDaw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo
Daw1b2b1584Clo/Daw1b2b1584CloC57BL/6J-Daw1b2b1584Clo

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory