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Phenotype Images associated with this Allele
Nomenclature
Symbol: Daw1b2b1116Clo
Name: dynein assembly factor with WDR repeat domains 1; Bench to Bassinet Program (B2B/CVDC), mutation 1116 Cecilia Lo
MGI ID: MGI:5311383
Synonyms: Acorn
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Mutant 1116-027-NA presents with dextrocardia and inverted, parallel outflow which is diagnosed as overriding aorta by EFIC imagingDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
EFIC SummaryDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Serial 2D EFIC image stack in the coronal plane of 1116-027-NA reveals dextrocardia with overriding aorta
Click thumbnail to play movie.
Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-027-LA presents with microphthalmia of the right eyeDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-027-LA exhibits a malaligned sternumDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-027-LA exhibits a hypoplastic spleen, left-sided pancreas and spleen while the stomach is right-sidedDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-100-LA exhibits situs inversus totalis with dextrocardia and dextrogastriaDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
EFIC SummaryDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Serial 2D EFIC image stack in the coronal plane of 1116-100-LA reveals mirror image dextrocardia
Click thumbnail to play movie.
Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-027-LA presents with heterotaxy with dextrocardia, dual IVC, normal liver lobation, and dextrogastriaDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
EFIC SummaryDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Serial 2D EFIC image stack in the coronal plane of 1167-027-LA reveals dextrocardia, pmVSD, and dual IVC
Click thumbnail to play movie.
Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-006-LA exhibits left lung isomerism (2R/1L)Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
EFIC SummaryDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Serial 2D EFIC image stack in the coronal plane of 1116-060-LA reveals hypoplastic right ventricle, hypoplastic PA, and pmVSD
Click thumbnail to play movie.
Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-060-LA exhibits heterotaxy with dextrogastria and hypoplastic spleenDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-060-LA presents with a malaligned sternumDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-060-LA exhibits immotile and dyskinetic airway cilia
Click thumbnail to play movie.
Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Mutant 1116-037-LA exhibits heterotaxy with dextrocardia, inverted lung and liver lobation, and left-sided stomachDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
EFIC SummaryDaw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo
Serial 2D EFIC image stack in the coronal plane of 1167-037-LA reveals mirror image dextrocardia
Click thumbnail to play movie.
Daw1b2b1116Clo/Daw1b2b1116CloC57BL/6J-Daw1b2b1116Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory