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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dnaic1b2b284Clo
Name: dynein, axonemal, intermediate chain 1; Bench to Bassinet Program (B2B/CVDC), mutation 284 Cecilia Lo
MGI ID: MGI:5285080
Synonyms: Bishu, Dnaic1IVS4+1G-A
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Dextrocardia with parallel outflow tracts suggestive of DORV (confirmed by EFIC imaging).Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Heterotaxy is indicated by dextrocardia and levogastriaDnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Coronal movie obtained by micro-CT scan reveals dextrocardia {ILL}, TGA, and inverted lung lobation pattern
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Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
EM micrograph reveals missing ODA within tracheal airway ciliaDnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
3D EFIC imaging movie reveals situs inversus totalis {I,L,I}
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Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
2D serial EFIC image stacks in the coronal view reveals DORV {A,L,L} and AVSD
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Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Ultrasound imaging in the four-chamber view reveals AVSD
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Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Ultrasound imaging in four-chamber view reveals AVSD
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Ultrasound imaging in sagittal view reveals DORV and VSD
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Ultrasound imaging in four-chamber view reveals AVSDDnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Ultrasound imaging in four-chamber view reveals AVSDDnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Ultrasound imaging in the sagittal view reveals DORV and VSDDnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Coronal movie obtained by micro-CT scan reveals DORV {ALL}, uncommitted VSDs, common AV valve and IAA (type-B)
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Transverse movie obtained by micro-CT scan reveals uncommitted VSDs and common AV valve
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Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
2D serial EFIC image stacks in the transverse view reveals DORV, ambiguous atria and AVSD
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Videomicroscopy of tracheal airway cilia reveals largely immotile cilia with a few showing slow dyskinetic twitching
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Videomicroscopy of tracheal airway cilia reveals largely immotile cilia with a few showing slow dyskinetic twitching
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
Transverse movie obtained by micro-CT scan reveals dextrocardia {ILL}, TGA, and intact ventricular septum
Click thumbnail to play movie.
Dnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo
EFIC imaging reveals DORV, right aortic arch, ASD, AVSD, VSDs, and preductal arch hypoplasiaDnaic1b2b284Clo/Dnaic1b2b284CloC57BL/6J-Dnaic1b2b284Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory