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Phenotype Images associated with this Allele
Nomenclature
Symbol: Hbbtm1.1(HBG1,HBB*)Ryan
Name: hemoglobin beta chain complex; targeted mutation 1.1, Thomas M Ryan
MGI ID: MGI:3843171
Synonyms: gamma beta0
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+ mice have a severe Beta Thalassemic phenotypeHbbtm1.1(HBG1,HBB*)Ryan/Hbb+involves: C57BL/6J
Appearance of Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+ miceHbbtm1.1(HBG1,HBB*)Ryan/Hbb+involves: C57BL/6J
Erythroid hyperplasia in bone marrow, increased iron deposition in the liver, and alpha globin chain inclusions in the peripheral blood of Hbbtm1.1(HBG1,HBB*)Ryan/Hbb+ miceHbbtm1.1(HBG1,HBB*)Ryan/Hbb+involves: C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory