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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ncor2tm1Rev
Name: nuclear receptor co-repressor 2; targeted mutation 1, Ronald M Evans
MGI ID: MGI:3829987
Synonyms: SMRTmRID, SMRTmRID1
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Defective bone growth in Ncor2tm1Rev/Ncor2tm1Rev miceNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Increased numbers of osteoclasts along the endosteal surface in Ncor2tm1Rev/Ncor2tm1Rev miceNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Splenomegaly in Ncor2tm1Rev/Ncor2tm1Rev miceNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Bones from Ncor2tm1Rev/Ncor2tm1Rev mice are paleNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Increased numbers of megakaryocytes in bone marrow and spleen of Ncor2tm1Rev/Ncor2tm1Rev miceNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Increase in nonhematopoietic cells, and osteosclerosis and microvessel formation in Ncor2tm1Rev/Ncor2tm1Rev bone marrowNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Marrow cavity is occupied by reticular cells in Ncor2tm1Rev/Ncor2tm1Rev miceNcor2tm1Rev/Ncor2tm1Revinvolves: 129/Sv * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory