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Phenotype Images associated with this Allele
Nomenclature
Symbol: Lipatm1Ggb
Name: lysosomal acid lipase A; targeted mutation 1, Gregory A Grabowski
MGI ID: MGI:2451080
Synonyms: lal-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lipid storage in the liver and small intestine and decrease in subcutaneous white adipose tissue in Lipatm1Ggb/Lipatm1Ggb mice as they ageLipatm1Ggb/Lipatm1Ggbinvolves: 129P2/OlaHsd * CF-1
Lipid storage cells in Lipatm1Ggb/Lipatm1Ggb mouse liver are nonhepatocytesLipatm1Ggb/Lipatm1Ggbinvolves: 129P2/OlaHsd * CF-1
Progressive loss of brown and white adipose tissue in Lipatm1Ggb/Lipatm1Ggb miceLipatm1Ggb/Lipatm1Ggbinvolves: 129P2/OlaHsd * CF-1
Proliferation of hepatocytes and Kupffer cells in Lipatm1Ggb/Lipatm1Ggb miceLipatm1Ggb/Lipatm1Ggbinvolves: 129P2/OlaHsd * CF-1
Subcellular localization of lipid storage in the liver of Lipatm1Ggb/Lipatm1Ggb miceLipatm1Ggb/Lipatm1Ggbinvolves: 129P2/OlaHsd * CF-1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/03/2022
MGI 6.21
The Jackson Laboratory