About   Help   FAQ
Phenotype Image Detail
Image
Caption Impact of DREC deletion on dioxin-induced toxicity. (D and E) MGI:3840320/MGI:3840320 (DREC-/-) mice were given a single injection of DMSO or 64 ug/kg of dioxin and were killed 5 days later. Liver sections were stained with H&E and immunostained with F4/80 antibody. (D) H&E. The black arrowhead indicates the region of hydropic degeneration; * indicates focal inflammation. (Magnification: X100.) (a) WT given dioxin. (Magnification: X400.) (b) MGI:3840320/MGI:3840320 (DREC-/-) given dioxin. (Magnification: X400.) (E) F4/80. The brown spots indicate F4/80-positive cells. (Magnification: X100.)
Copyright This image is from Nukaya M, Proc Natl Acad Sci U S A 2009 Mar 24;106(12):4923-8. Copyright 2009 National Academy of Sciences, U.S.A. J:147150
Associated
Alleles
Symbol Name
Cyp1atm1.1Bra cytochrome P450, family 1, subfamily a cluster; targeted mutation 1.1, Christopher A Bradfield
Associated
Genotypes
Allelic Composition Genetic Background
Cyp1atm1.1Bra/Cyp1atm1.1Bra B6.129-Cyp1atm1.1Bra
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory