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Phenotype Image Detail
Image
Caption Photograph of a 10-day-old Paxxem1Spj/Paxxem1Spj Nhej1tm1Fwa/Nhej1tm1Fwa (Paxx-/- Xlf-/-) mouse as compared with a littermate control, Nhej1tm1Fwa/Nhej1tm1Fwa (Xlf-/-) mouse. Isolated spleens and thymus of the represented mice are shown. In the case of the double mutant mouse no thymus was identified.
Copyright This image is from Balmus G, Genes Dev 2016 Oct 1;30(19):2152-2157, and is displayed with the permission of Cold Spring Harbor Laboratory Press, who owns the Copyright. J:236776
Associated
Alleles
Symbol Name
Nhej1tm1Fwa non-homologous end joining factor 1; targeted mutation 1, Frederick W Alt
Paxxem1Spj non-homologous end joining factor; endonuclease-mediated mutation 1, Stephen P Jackson
Associated
Genotypes
Allelic Composition Genetic Background
Paxxem1Spj/Paxxem1Spj
Nhej1tm1Fwa/Nhej1tm1Fwa
involves: 129S6/SvEvTac * C57BL/6NTac

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory