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| Caption | The embryonic lethality of Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg mice can be partially rescued by concomitant loss of Trp53. Representative E9.5 embryos (with genotypes indicated) from intercross between male Cops6Gt(RRI087)Byg/Cops6+ Trp53tm1Glo/Trp53tm1Glo and female Cops6Gt(RRI087)Byg/Cops6+ Trp53tm1Glo/Trp53+ mice are shown. Trp53tm1Glo/Trp53tm1Glo embryos cannot be detected at E9.5 but Cops6Gt(RRI087)Byg/Cops6Gt(RRI087)Byg Trp53tm1Glo/Trp53tm1Glo (Csn6-/-;p53-/-) embryos can be identified at this embryonic stage. Note that these embryos were less developed (panel E) or much smaller (panel F) when compared to other embryos. | ||||||
| Copyright | This image is from Zhao R, J Clin Invest 2011 Mar 1;121(3):851-65 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172038 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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