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Phenotype Image Detail
Image
Caption Unilateral and bilateral kidney agenesis in Lrp4tm2Her/Lrp4tm2Her mice. Kidney agenesis in the knockout (b,d,e). Bilateral (b,d) or unilateral (e) kidney agenesis with rudimentary ureters (red arrows). The lower urinary and genital systems of males and females remain intact. Histological analysis (Hematoxylin-Eosin stain) does not reveal morphological defects in the kidneys that form in knockout animals (g) compared to the wild-type kidneys (f).
Copyright This image is from Karner CM, PLoS One 2010;5(4):e10418, an open-access article distributed under the terms of the Creative Commons Attribution License. J:160547
Associated
Alleles
Symbol Name
Lrp4tm2Her low density lipoprotein receptor-related protein 4; targeted mutation 2, Joachim Herz
Associated
Genotypes
Allelic Composition Genetic Background
Lrp4tm2Her/Lrp4tm2Her involves: 129S/SvEv * C57BL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory