About   Help   FAQ
Phenotype Image Detail
Image
Caption Histological analysis of the microcystic adenomas (MCA) which developed in Vhltm1Lss/Vhltm1Lss Tg(Pdx1-cre)89.1Dam/0 (Pdx1-Cre;Vhl f/f) adult pancreas. A. H&E staining of pancreas from representative control Tg(Pdx1-cre)89.1Dam/0 (Pdx1-Cre; panel a), and Vhltm1Lss/Vhl+ (Vhl f/+; panel d) mice and two different Vhltm1Lss/Vhltm1Lss Tg(Pdx1-cre)89.1Dam/0 (Pdx1-Cre;Vhl f/f; panels b, c, e, and f) mice at 16-18 months of age. Gross pancreas histology is shown at 40x in panels a, b, d, e, and areas (black boxes) in panels b and e are magnified at 200x in panels c and f. Islets are indicated by arrows and MCA are indicated by asterisk.
Copyright This image is from Shen HC, PLoS ONE 2009;4(4):e4897, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:148174
Associated
Alleles
Symbol Name
Tg(Pdx1-cre)89.1Dam transgene insertion 89.1, Douglas A Melton
Vhltm1Lss von Hippel-Lindau tumor suppressor; targeted mutation 1, Laura S Schmidt
Associated
Genotypes
Allelic Composition Genetic Background
Vhltm1Lss/Vhltm1Lss
Tg(Pdx1-cre)89.1Dam/0
involves: 129X1/SvJ * C57BL/6 * CBA

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory