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Phenotype Image Detail
Image
Caption Increase of creatine in hippocampus of Tg(PRNP-APPSweInd)8Dwst/0 (Transgenic) mouse with age. Fourier transform infrared Focal plane array (FTIR-FPA) maps of hippocampal tissue from littermate control and mutant mice, sacrificed at 5, 8, 11, 14, and 17 months are shown. Age of littermate pair in months is shown in the upper left corner of first processed image in each row. Each map has been processed for the band areas of lipid carbonyl and of creatine. Relative amounts are portrayed as gray scale using one set of limits for total lipid and one for total creatine. Creatine deposits are concentrated over the pyramidal cell layer of the hippocampus formation. Scale bar, 100 um.
Copyright This image is from Kuzyk A, J Biol Chem 2010 Oct 8;285(41):31202-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166801
Associated
Alleles
Symbol Name
Tg(PRNP-APPSweInd)8Dwst transgene insertion 8, David Westaway
Associated
Genotypes
Allelic Composition Genetic Background
Tg(PRNP-APPSweInd)8Dwst/0 involves: C3H/HeJ * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory