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Phenotype Image Detail
Image
Caption Murine ABHD5 (CGI-58) deficiency causes neutral lipid storage disease (NLSD) with ichthyosis. A, Photograph of newborn wild-type and Abhd5tm1.1Rze/Abhd5tm1.1Rze (Cgi-58-/-) mice. Note the glossy dry skin, the smaller size of the body, and necrotic tail tip.
Copyright This image is from Radner FP, J Biol Chem 2010 Mar 5;285(10):7300-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:160725
Associated
Alleles
Symbol Name
Abhd5tm1.1Rze abhydrolase domain containing 5; targeted mutation 1.1, Rudolf Zechner
Associated
Genotypes
Allelic Composition Genetic Background
Abhd5tm1.1Rze/Abhd5tm1.1Rze involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory