About   Help   FAQ
Phenotype Image Detail
Image
Caption (A) Wild-type (+/+), Ptrh2tm1.1Eruo/Ptrh2+ (+/-), and Ptrh2tm1.1Eruo/Ptrh2tm1.1Eruo (KO) embryos delivered by C-section are shown. (B) Representative mutant and wild-type littermate mice are depicted in dorsal and side shots at approximately P10. (C and D) Mutant mice exhibit delayed development. H&E stained sections of the kidney (C) and the muscle (D). The glomeruli are smaller in the kidney than in wild-type control. A representative glomerulus is encircled. The fibers are smaller in epaxial muscle in the mutant mice. This size difference was particularly striking for the older mice (P<0.001; one-way ANOVA and Tukey test). (Size bars: 50 um).
Copyright This image is from Kairouz-Wahbe R, Proc Natl Acad Sci U S A 2008 Feb 5;105(5):1528-32. Copyright 2008 National Academy of Sciences, U.S.A. J:131853
Associated
Alleles
Symbol Name
Ptrh2tm1.1Eruo peptidyl-tRNA hydrolase 2; targeted mutation 1.1, Erkki Ruoslahti

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory