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Phenotype Image Detail
Image
Caption Histology of the descending colon. The two panels at top depict the histology of the full thickness of the wall of colons extirpated from wild-type (WT) mice fed normal laboratory chow (top left) and from Gfustm1Jbl/Gfustm1Jbl (FX(-/-)) mice fed fucose-supplemented chow (2.5% wt/wt) (top right). The wall of the colon in mutant mice reared in the absence of fucose is roughly twice the normal thickness, necessitating separate panels that display the basal (bottom left) and the lumenal (bottom right) aspects of the fucose-deficient mutant colon wall. Black arrows identify crypt abscesses. Red arrows delimit areas of mixed inflammatory cell infiltrate that expand the lamina propria, including a plasma cell infiltrate beneath the base of and between crypts. Hematoxylin and eosin stain.
Copyright This image is from Smith PL, J Cell Biol 2002 Aug 19;158(4):801-15, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:82239
Associated
Alleles
Symbol Name
Gfustm1Jbl GDP-L-fucose synthase; targeted mutation 1, John Lowe
Associated
Genotypes
Allelic Composition Genetic Background
Gfustm1Jbl/Gfustm1Jbl involves: 129S2/SvPas * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory