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Phenotype Image Detail
Image
Caption (a) 1 day old Krt10tm1Tmm/Krt10tm1Tmm mouse. Homozygous mutant mice exhibit large areas of skin loss. Krt10tm1Tmm/Krt10+ mice (H) showed extensive hyperkeratotic scaling of the skin on the tail (b), paws (c), and ears (d). A wild-type (W) littermate is shown on the left of each picture for comparison. Both mice were ~2 months old.
Copyright This image is from Porter RM, J Cell Biol 1996 Mar;132(5):925-36, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:31853
Associated
Alleles
Symbol Name
Krt10tm1Tmm keratin 10; targeted mutation 1, Thomas M Magin
Associated
Genotypes
Allelic Composition Genetic Background
Krt10tm1Tmm/Krt10tm1Tmm either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6)
Krt10tm1Tmm/Krt10+ either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * BALB/c * C57BL/6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory