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Phenotype Image Detail
Image
Caption Situs anomalies in Dnah5hlb612/Dnah5hlb612 mice. A: Situs solitus with levocardia. The right lung (R) has 4 lobes, and the left lung (L) has 1. Arrow indicates directions of heart (H) apex. The stomach (S) is on the left. B: Situs inversus totalis with dextocardia. Note 4 left (labeled 1, 2, 3, and 4) and 1 right (R1), lung lobes, with stomach on the right. C and D: Heterotaxy with levocardia. Note right aortic arch (RAA), 1 lung lobe on each side (R1 and L1), and stomach on the right (C). After removal of the liver, azygos continuation (arrowhead) of the interrupted inferior vena was found (D). K, kidney. Scale bar: A-D, 250mm.
Copyright This image is from Tan SY, J Clin Invest 2007 Dec;117(12):3742-52 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:130755
Associated
Alleles
Symbol Name
Dnah5hlb612 dynein, axonemal, heavy chain 5; heart, lung and blood 612
Associated
Genotypes
Allelic Composition Genetic Background
Dnah5hlb612/Dnah5hlb612 involves: C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory