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| Caption | Whole mount hearts from 2 month old wild type (a), Destm1Cap/Destm1Cap (b), Destm1Cap/Destm1Cap Tg(Bcl2)ACap/Tg(Bcl2)ACap (c) and Destm1Cap/Destm1Cap Tg(Bcl2)BCap/Tg(Bcl2)BCap (d) mice. (e-h) Hematoxylin and eosin stained sections from the same genotype mice. (i-p) Fibrosis associated with calcium deposits is found throughout the left ventricle of Destm1Cap/Destm1Cap hearts, as revealed by Mason's trichrome staining (j & n). Compared to Destm1Cap/Destm1Cap, fibrotic lesions are less frequent and smaller in Destm1Cap/Destm1Cap Tg(Bcl2)ACap/Tg(Bcl2)ACap (k) and Destm1Cap/Destm1Cap Tg(Bcl2)BCap/Tg(Bcl2)BCap (l) mice. Although calcification is obvious in Von Kossa staining of Destm1Cap/Destm1Cap myocardium (n), there is less calcification of lesions in Destm1Cap/Destm1Cap Tg(Bcl2)BCap/Tg(Bcl2)BCap hearts (p). Magnification x200. | ||||||||
| Copyright | This image is from Weisleder N, Proc Natl Acad Sci U S A 2004 Jan 20;101(3):769-74. Copyright 2004 National Academy of Sciences, U.S.A. J:88267 | ||||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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