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Phenotype Image Detail
Image
Caption A & B: Frem1bat/Frem1bat mice display cryptophthalmos in adults and embryonic blebs from about 13.5 dpc, which invariably affect the developing eyes (B, arrowheads). C: Sectioning at 16.5 dpc illustrates the formation of a pseudoblepharon (arrowheads), which severely affects development of the underlying eyelids. D: The epidermis (ep) in the blebs of mutant embryos separates from the dermis below the lamina lucida (ll) and the lamina densa (ld) of the basement membrane. The resulting blister cavity (bc) contains residual anchoring fibrils on the subepidermal face.
Copyright This image is from Smyth I, Proc Natl Acad Sci U S A 2004 Sep 14;101(37):13560-5. Copyright 2004 National Academy of Sciences, U.S.A. J:92613
Associated
Alleles
Symbol Name
Frem1bat Fras1 related extracellular matrix protein 1; bat
Associated
Genotypes
Allelic Composition Genetic Background
Frem1bat/Frem1bat C57BL/6J-Frem1bat

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory