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| Caption | A & B: Frem1bat/Frem1bat mice display cryptophthalmos in adults and embryonic blebs from about 13.5 dpc, which invariably affect the developing eyes (B, arrowheads). C: Sectioning at 16.5 dpc illustrates the formation of a pseudoblepharon (arrowheads), which severely affects development of the underlying eyelids. D: The epidermis (ep) in the blebs of mutant embryos separates from the dermis below the lamina lucida (ll) and the lamina densa (ld) of the basement membrane. The resulting blister cavity (bc) contains residual anchoring fibrils on the subepidermal face. | ||||
| Copyright | This image is from Smyth I, Proc Natl Acad Sci U S A 2004 Sep 14;101(37):13560-5. Copyright 2004 National Academy of Sciences, U.S.A. J:92613 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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