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Phenotype Image Detail
Image
Caption Light microscopy of livers in 17.5dpc Adatm1Mw/Ada+ and Adatm1Mw/Adatm1Mw mice. A: Liver in Adatm1Mw/Ada+ fetuses has normal sized hepatocytes with centrally located nuclei and granular or vacuolated cytoplasm (arrows). Extramedullary hematopoiesis characterized by megakaryocytes (m) and erythrocytic or granulocytic precursor cells (arrowheads) can be seen in the hepatic sinusoids. B: Adatm1Mw/Adatm1Mw fetus with enlarged hepatocytes (arrows) and marked extramedullary hematopoiesis in sinusoids adjacent to affected hepatocytes (arrowheads)> Scale bar: 32um
Copyright This image is from Wakamiya M, Proc Natl Acad Sci U S A 1995 Apr 25;92(9):3673-7. Copyright 1995 National Academy of Sciences, U.S.A. J:25085
Associated
Alleles
Symbol Name
Adatm1Mw adenosine deaminase; targeted mutation 1, Maki Wakamiya
Associated
Genotypes
Allelic Composition Genetic Background
Adatm1Mw/Adatm1Mw involves: 129S7/SvEvBrd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory