| Image |
|
||||
| Caption | Parasagittal sections of E18.5 cerebellum with anterior to the left and dorsal to the top. (A and B) Nissl staining. The EGL (arrows) of wild-type cerebellum (A) lies between the meninges and the diffuse Purkinje cell layer (partially marked by arrowheads). The abnormal cerebellum in Cxcr4tm1Qma/Cxcr4tm1Qma mice (B) has an irregular EGL (arrows) and large chromophilic cell clumps within the cerebellar anlage. (C and D) Calbindin immunohistochemistry. In comparison with the Purkinje cell layer (arrowheads) in wild-type cerebellum (C), Purkinje cells are located ectopically (arrow) in the homozygous mutant cerebellum (D). (E-I) Chromophilic cell clumps in homozygous mutant cerebellar anlage. Streaming cells from the EGL (E). Combined Nissl and calbindin staining (F). Purkinje cell neurites do not extend into the clumps (asterisks) (G). Adjacent sections stained by Nissl technique (H) or BrdUrd incorporation (I). Scale bar: A-D: 200um; E-H: 50um | ||||
| Copyright | This image is from Ma Q, Proc Natl Acad Sci U S A 1998 Aug 4;95(16):9448-53. Copyright 1998 National Academy of Sciences, U.S.A. J:49070 | ||||
|
Associated Alleles |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools