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Phenotype Image Detail
Image
Caption A-D: Hematoxylin and eosin stained liver and spleen sections from wild type and Tnftm1Ljo/Tnftm1Ljo mice 10 days after C. parvum treatment showing characteristic inflammatory responses in liver (A) and spleen (C) of wild type mice, and the absence of these responses and the preserved architecture of liver (B) and spleen (D) of the homozygous mutant mice. E-H: Liver and spleen sections from mice 40 days after C. parvum treatment showing the almost natural morphology typical of the down-regulated inflammatory response in liver parenchyma (E) and spleen (G) of wild type mice, and the late inflammatory infiltration in liver (F) and spleen (H) of the homozygous mutant mice.
Copyright This image is from Marino MW, Proc Natl Acad Sci U S A 1997 Jul 22;94(15):8093-8. Copyright 1997 National Academy of Sciences, U.S.A. J:41992
Associated
Alleles
Symbol Name
Tnftm1Ljo tumor necrosis factor; targeted mutation 1, Lloyd J Old
Associated
Genotypes
Allelic Composition Genetic Background
Tnftm1Ljo/Tnftm1Ljo involves: 129S1/Sv

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory