About   Help   FAQ
Phenotype Image Detail
Image
Caption A: X-ray image of a 5 week old wild-type (left) and Smpd3tm1Wst/Smpd3tm1Wst (right) littermates. The long bones of the homozygous mouse are proportionally shorter, and the bone structure is more translucent. Arrows, multiple deformations of femur, tibia and fibula. B: Cortices of tibia shafts of male wild-type and homozygous mice at 6 weeks of age. The red bar points to the different thickness of cortices. C & D: Proximal tibia of wild-type (C) and homozygous mutant (D) mice sections. Abbreviations: growth plate (gp); hypertrophic zone (hz); secondary ossification center (oc); vascular buds (vb) Magnification: x40 Scalebar: 7um
Copyright This image is from Stoffel W, Proc Natl Acad Sci U S A 2005 Mar 22;102(12):4554-9. Copyright 2005 National Academy of Sciences, U.S.A. J:97284
Associated
Alleles
Symbol Name
Smpd3tm1Wst sphingomyelin phosphodiesterase 3, neutral; targeted mutation 1, Wilhelm Stoffel
Associated
Genotypes
Allelic Composition Genetic Background
Smpd3tm1Wst/Smpd3tm1Wst involves: 129S1/Sv

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory