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Phenotype Image Detail
Image
Caption Histological sections of decalcified tibiae from newborn mouse homozygous for Tg(Col2a1-PTHR1*H223R)AHju (A), mouse homozygous for both Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk (B), and a mouse homozygous for Pthlhtm1Hmk (C). The sections were stained with hematoxylin and eosin. THe height of the proliferative chondrocyte layer is indicated by brackets. A-C show pictures at the same magnification. Pthlhtm1Hmk
Copyright This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
Associated
Alleles
Symbol Name
Pthlhtm1Hmk parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHR1*H223R)AHju transgene insertion A, Harald Juppner
Associated
Genotypes
Allelic Composition Genetic Background
Pthlhtm1Hmk/Pthlhtm1Hmk involves: 129S2/SvPas * C57BL/6
Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju involves: C57BL/6
Pthlhtm1Hmk/Pthlhtm1Hmk
Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju 		involves: 129S2/SvPas * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory