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Phenotype Image Detail
Image
Caption Panels A and C represent skin tumor-free mice after chronic treatment. Solid bar represents exposure period for all animals, dotted bar represents exposure period for tumor-free only. Panels B and D represent tumor numbers per mouse after chronic treatment. Solid bar represents exposure period for all animals and dotted bar represents exposure period for tumor-free only. Panel E is a typical example of squamous cell carcinoma found in Ddb2tm1Linn/Ddb2tm1Linn mice, squamous and inflammatory cells are present (arrow). Panel F indicates mitotic figures. Panel G is a typicall example of pappilloma
Copyright This image is from Itoh T, Proc Natl Acad Sci U S A 2004 Feb 17;101(7):2052-7. Copyright 2004 National Academy of Sciences, U.S.A. J:88125
Associated
Alleles
Symbol Name
Ddb2tm1Linn damage specific DNA binding protein 2; targeted mutation 1, Stuart Linn
Associated
Genotypes
Allelic Composition Genetic Background
Ddb2tm1Linn/Ddb2tm1Linn involves: 129S/SvEv * C57BL/6
Ddb2tm1Linn/Ddb2+ involves: 129S/SvEv * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory