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Caption Generation of the Mir33tm1.1Koho allele. (A) Strategy to generate miR-33-deficient mice by homologous recombination. The premiR-33 sequence was replaced with a neomycin resistance cassette (pgk-gb2-Neo) flanked by loxP sites. The neomycin resistance cassette was removed in the mouse germ line by breeding heterozygous mice with Ayu-1 Cre mice, which express Cre recombinase in multiple tissues, including the germ line.
Copyright This image is from Horie T, Proc Natl Acad Sci U S A 2010 Oct 5;107(40):17321-6. Copyright 2010 National Academy of Sciences, U.S.A. J:165420
Associated
Alleles
Symbol Name
Mir33tm1.1Koho microRNA 33; targeted mutation 1.1, Koh Ono

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/28/2022
MGI 6.20
The Jackson Laboratory