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Molecular Image Detail
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Caption Generation of the Col5a3tm1Dgr allele. (A) Structure of the targeting vector and Col5a3 locus, before and after homologous recombination. Horizontal arrows mark directions of transcription of neor and tk cassettes. Blue, red, and hatched boxes represent COL1, C-propeptide, and 3'-UTR exons, respectively. The green boxes represent the Neor cassette; the yellow boxes represent 5' and 3' external probes. The asterisks mark the site of a premature stop codon engineered via blunt-end ligation of a NarI site. A, AflII; N, NarI.
Copyright This image is from Huang G, J Clin Invest 2011 Feb 1;121(2):769-83 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171817
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Col5a3tm1Dgr collagen, type V, alpha 3; targeted mutation 1, Daniel S Greenspan

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory