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| Caption | Generation of the Juptm1.1Chen allele. A Schematic of the original Naxos construct. Exons are depicted in blue, flipase sites are denoted as black rectangles. Red and green rectangles denote the exons with the TG deletion and premature stop codons, respectively. Note the removal of 2 base pairs (bps) (TG) denoted in blue from the wild-type (WT) allele and mutation of the indicated bps (green) to modify the mouse genome to exactly mimic the human mutation found in Naxos disease. | ||||
| Copyright | This image is from Zhang Z, J Clin Invest 2015 Apr;125(4):1708-12 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:222025 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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