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| Caption | (A) "Porcn locus" represents the wild-type (WT) locus; "Targeted Allele" contains loxP sites in introns 2 and 7 and an FRT-flanked neomycin (Neo) gene in intron 7 (Porcn-ex3-7-Neo-flox), generating the Porcntm1Vdv allele; "Floxed Allele" retains only loxP sites after excision of Neo (Porcn-ex3-7flox) and generates the Porcntm1.1Vdv allele; "Deleted Allele" lacks exons 3 through 7 (Porcn-ex3-7del) and gives rise to the Porcntm1.2Vdv allele. P1-P4 indicate the location of the various genotyping primers; blue boxes represent the probes for sourthern analysis; E = EcoRI and S = ScaI restriction sites; sizes for diagnostic fragments for southern analysis are also shown. | ||||||||
| Copyright | This image is from Liu W, PLoS One 2012;7(3):e32331, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:186934 | ||||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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