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| Caption | (A) The targeting vector inserted a FRT-flanked neo cassete with a 3' loxP site upstream of exon 2 and an additional loxP site downstream of exon 3, to generate the Ppm1atm1Xya allele (Targeted Allele). The targeting vector deleted a 6 kb genomic sequence containing exons 2 and 3 with the translation start codon (ATG) of Ppm1a to generate the Ppm1atm1.1Xya allele (Knockout Allele). The 3' external probe for Southern blot analysis was indicated. Arrows indicated positions of genotyping primers. | ||||||
| Copyright | This image is from Yang X, J Biol Chem 2011 Dec 9;286(49):42267-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:178733 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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