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| Caption | (A) Schematic representation of the murine Mfrp/C1qtnf5 genes. Boxes represent exons, the solid line represents intronic sequence (not drawn to scale). B) The targeting construct to generate the C1qtnf5tm1.1Geno allele showing the long (6.8 kb) homology arm (LA), short (1.4 kb) homology arm (SA) and the central fragment with the Ser163Arg mutation labelled with a *. FRT: Flippase Recognition Target sites, Neo: the neomycin selection cassette. LoxP; sites flanking the introduced mutation and Neo gene, allowing subsequent Cre-recombinase-mediated deletion to generate a knockout mouse. | ||||
| Copyright | This image is from Shu X, PLoS One 2011;6(11):e27433, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:180961 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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